Abstract GS3-03: Randomized controlled trial of Young, Empowered & Strong (YES), an mHealth intervention for adolescent and young adult breast cancer survivors

Clinical Cancer Research 2026

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Authors: A. H. Partridge, Noah Graham, K. E. Dibble, Nabihah Tayob, Y. Zheng, E. J. Johnson, Chloe M. Beverly Hery, K. Williams, Sonja Darai, E. F. Harden, M. M. Durant, A. Davenport
+9 more C. R. Degraffinreid, T. S. Nolan, Magnolia Contreras, Noel D Roma, S. A. Mitchell, D. Schrag, Dawn L. Hershman, S. M. Rosenberg, M. J. Naughton
DOI: 10.1158/1557-3265.sabcs25-gs3-03
Cited by: 1

Abstract

Abstract Background: Adolescent and young adult (AYA) breast cancer (BC) survivors may experience substantial symptoms and concerns. Serial monitoring using electronic patient-reported outcomes (ePROs) has improved outcomes for adults receiving chemotherapy but it is uncertain whether ePRO monitoring improves symptom burden and quality of life (QOL) in survivor populations including AYAs. Methods: We conducted a multicenter randomized controlled trial of YES, an mHealth web and app-based intervention which offers (i) tailored information, resources and support based on monthly ePRO surveillance, together with (ii) an expressive writing platform, and (iii) a monitored chat room. Intervention components are designed to engage and activate AYA BC survivors to self-manage their symptoms and concerns. Participants (age

Fields of Study & Subjects

Childhood Cancer Survivors' Quality of Life Cancer survivorship and care Advanced Breast Cancer Therapies

Publication details

Journal / source
Clinical Cancer Research
Publisher
American Association for Cancer Research (AACR)
Volume
32
Issue
4_Supplement
Pages
GS3–03
Publication date
17 February 2026
Language
EN