Abstract PS1-07-04 : Ct simulation as a missed opportunity? coronary artery calcifications predict risk of coronary events in older breast cancer patients

Abstract Introduction: Coronary artery calcifications (CAC) are frequently visible on CT simulation scans performed for radiotherapy planning in breast cancer patients. These women often have elevated cardiovascular risk, exacerbated by cancer therapies such as chemotherapy (including anthracyclines, and cyclophosphamide), aromatase inhibitors, trastuzumab, ovarian suppression and radiation. Despite this, routine cardiovascular evaluation is uncommon. As CT simulation may be the only imaging that reveals coronary anatomy, it offers a unique opportunity for radiation oncologists to identify high-risk patients, yet no guidelines exist on how to interpret or act upon these findings. Methods: We conducted a retrospective cohort study of breast cancer patients aged ≥65 treated with radiotherapy at a single tertial care cancer center 2017. Patients were excluded if they were