PS5-10-27: Integrating Virtual Collaborative Care Behavioral Health in Breast Cancer Care: Improving Outcomes in Mental Health, Adherence, and Racial Equity

Abstract Background: Patients with breast cancer often experience depression, anxiety, and reduced quality of life during treatment, yet mental health support is rarely integrated into oncology care. While collaborative care models have demonstrated efficacy in primary care, their impact in oncology remains under-explored. This study evaluated the impact of Cerula Care, a virtual collaborative care program, on mental health and quality of life among patients with breast cancer. Methods: We conducted a retrospective analysis of 207 patients with breast cancer enrolled in a virtual behavioral health program (Cerula Care) integrated into their oncology care. Patients received coordinated care from a psychiatrist, behavioral health care manager, and behavioral health coach. Depression (PHQ-9), anxiety (GAD-7), and quality of life (FACT-G7) were assessed monthly. Changes in outcomes were analyzed using paired-sample t-tests and correlations. Results: Participants were predominantly female (99%), with a mean age of 55.7 years; 58% identified as White and 32.4% as Black/African American. Medicaid patients had statistically significant higher anxiety and depression at baseline (GAD-7 mean = 10.67 vs. 6.62, p = .005), (PHQ-9 mean = 10.62 vs. 7.63, p = .004), and lower directionally lower functioning (FACT-G7 mean = 11.67 vs. 17.30, p = .073) showing the importance of screening Medicaid members who face greater stressors. Statistically significant improvements across all patients were observed in depression scores by month five (-6.63 points, n=32, p