Figure S4 from Aryl Hydrocarbon Receptor Ligands Drive Pancreatic Cancer Initiation and Progression through Protumorigenic T-cell Polarization

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Authors: Brian D. Griffith, Padma Kadiyala, Jake J. McGue, Lei Sun, Aadith Kumar, Carlos E. Espinoza, Katelyn L. Donahue, Matthew K. Iyer, Cameron B. Speyer, Sarah Nelson, A Spiteri, Ahmed M. Elhossiny
+9 more Kristee L. Brown, Holly Attebury, Filip Bednar, Eileen S. Carpenter, Ilona Kryczek, Yaqing Zhang, Weiping Zou, Marina Pasca di Magliano, Timothy L. Frankel
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Abstract

Supplementary Figure 4 shows histologic features of orthotic tumors placed in AhR knockout mice or those treated with an AhR inhibitor prior to TCDD administration.

Fields of Study & Subjects

Pancreatic and Hepatic Oncology Research Toxic Organic Pollutants Impact Cancer Stress Anesthesia and Immune Response

Publication details

Publication date
12 January 2026