Figure S3 from Aryl Hydrocarbon Receptor Ligands Drive Pancreatic Cancer Initiation and Progression through Protumorigenic T-cell Polarization

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Authors: Brian D. Griffith, Padma Kadiyala, Jake J. McGue, Lei Sun, Aadith Kumar, Carlos E. Espinoza, Katelyn L. Donahue, Matthew K. Iyer, Cameron B. Speyer, Sarah Nelson, A Spiteri, Ahmed M. Elhossiny
+9 more Kristee L. Brown, Holly Attebury, Filip Bednar, Eileen S. Carpenter, Ilona Kryczek, Yaqing Zhang, Weiping Zou, Marina Pasca di Magliano, Timothy L. Frankel
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Abstract

Supplementary Figure 3 shows gating strategies used for flow analysis of CD4 cells from orthotopic tumors as well as serum and tissue IL22 measured by ELISA. IHC and multiplex IHC analysis of TCDD treated tumors in the absence of T regulatory cells is shown.

Fields of Study & Subjects

Pancreatic and Hepatic Oncology Research T-cell and B-cell Immunology Immune cells in cancer

Publication details

Publication date
12 January 2026