Figure S2 from Sevabertinib, a Reversible HER2 Inhibitor with Activity in Lung Cancer

Franziska Siegel; Stephan Siegel; Kristýna Kotýnková; Gizem Karsli Uzunbas; Daniel Korr; Haruna Tomono; Sawyer Andersen; D.R. Denney; Markus Berger; Volker Schulze; Timothy A. Lewis; Bethany Kaplan; Sven Golfier; Jérémie Mortier; Roman Christian Hillig; Ulf Boemer; Kirstin Petersen; Knut Eis; Sybil M. Genther Williams; Dominik Rüttinger; Andrew D. Cherniack; Herbert Ho-Fung Loong; Koichi Goto; Paolo Grassi; Matthew M. Meyerson; Heidi E. Greulich

doi:10.1158/2159-8290.31047115

Figure S2 from Sevabertinib, a Reversible HER2 Inhibitor with Activity in Lung Cancer

2026 Open access

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Authors: Franziska Siegel, Stephan Siegel, Kristýna Kotýnková, Gizem Karsli Uzunbas, Daniel Korr, Haruna Tomono, Sawyer Andersen, D.R. Denney, Markus Berger, Volker Schulze, Timothy A. Lewis, Bethany Kaplan

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Sven Golfier, Jérémie Mortier, Roman Christian Hillig, Ulf Boemer, Kirstin Petersen, Knut Eis, Sybil M. Genther Williams, Dominik Rüttinger, Andrew D. Cherniack, Herbert Ho-Fung Loong, Koichi Goto, Paolo Grassi, Matthew M. Meyerson, Heidi E. Greulich

DOI: 10.1158/2159-8290.31047115

Cited by: 0

Abstract

Kinase inhibition of sevabertinib (1 μM) measured in the presence of 10 μM ATP

Fields of Study & Subjects

Lung Cancer Treatments and Mutations HER2/EGFR in Cancer Research Lung Cancer Research Studies

Publication details

Publication date: 12 January 2026