Figure S6 from EML4−ALK Variant-Specific Genetic Interactions Shape Lung Tumorigenesis

Alberto Diaz-Jimenez; Emily G. Shuldiner; Kálmán Somogyi; Karen Y. Shih; Óscar González-Velasco; Mulham Najajreh; Stewart J. Kim; Filiz Akkas; Christopher W. Murray; Laura Andrejka; Min K. Tsai; Benedikt Brors; Ilse Hofmann; Smruthy Sivakumar; Saumya Dushyant Sisoudiya; Ethan S. Sokol; Hongchen Cai; Dmitri A. Petrov; Monte M. Winslow; Rocı́o Sotillo

doi:10.1158/2159-8290.31047240

Figure S6 from EML4−ALK Variant-Specific Genetic Interactions Shape Lung Tumorigenesis

2026 Open access

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Authors: Alberto Diaz-Jimenez, Emily G. Shuldiner, Kálmán Somogyi, Karen Y. Shih, Óscar González-Velasco, Mulham Najajreh, Stewart J. Kim, Filiz Akkas, Christopher W. Murray, Laura Andrejka, Min K. Tsai, Benedikt Brors

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Ilse Hofmann, Smruthy Sivakumar, Saumya Dushyant Sisoudiya, Ethan S. Sokol, Hongchen Cai, Dmitri A. Petrov, Monte M. Winslow, Rocı́o Sotillo

DOI: 10.1158/2159-8290.31047240

Cited by: 0

Abstract

Supplementary Figure 6 show data on the adaptively sample mean size of tumors with each tumor suppressor gene inactivation at the sgRNA-level in the Lenti-sgTSG75-sgV1/Cre and Lenti-sgTSG75-sgV3/Cre pools in both Cas9EGFP and Cas9-negative control mice.

Fields of Study & Subjects

Lung Cancer Treatments and Mutations CRISPR and Genetic Engineering Lung Cancer Research Studies

Publication details

Publication date: 12 January 2026