Figure S4 from EML4−ALK Variant-Specific Genetic Interactions Shape Lung Tumorigenesis

2026 Open access

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Authors: Alberto Diaz-Jimenez, Emily G. Shuldiner, Kálmán Somogyi, Karen Y. Shih, Óscar González-Velasco, Mulham Najajreh, Stewart J. Kim, Filiz Akkas, Christopher W. Murray, Laura Andrejka, Min K. Tsai, Benedikt Brors
+8 more Ilse Hofmann, Smruthy Sivakumar, Saumya Dushyant Sisoudiya, Ethan S. Sokol, Hongchen Cai, Dmitri A. Petrov, Monte M. Winslow, Rocı́o Sotillo
DOI: 10.1158/2159-8290.31047246
Cited by: 0

Abstract

Supplementary Figure 4 shows data on the adaptively sample mean size of tumors with each tumor suppressor gene inactivation at the sgRNA-level in the Lenti-sgTSG19-sgV1/Cre and Lenti-sgTSG19-sgV3/Cre pools in both Cas9EGFP and Cas9-negative control mice.

Fields of Study & Subjects

Lung Cancer Treatments and Mutations CRISPR and Genetic Engineering Lung Cancer Research Studies

Publication details

Publication date
12 January 2026