Figure S2 from EML4−ALK Variant-Specific Genetic Interactions Shape Lung Tumorigenesis

2026 Open access

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Authors: Alberto Diaz-Jimenez, Emily G. Shuldiner, Kálmán Somogyi, Karen Y. Shih, Óscar González-Velasco, Mulham Najajreh, Stewart J. Kim, Filiz Akkas, Christopher W. Murray, Laura Andrejka, Min Kuan Tsai, Benedikt Brors
+8 more Ilse Hofmann, Smruthy Sivakumar, Saumya Dushyant Sisoudiya, Ethan S. Sokol, Hongchen Cai, Dmitri A. Petrov, Monte M. Winslow, Rocı́o Sotillo
DOI: 10.1158/2159-8290.31047252
Cited by: 0

Abstract

Supplementary Figure 2 show the increase tumorigenesis of V3 tumors in a different mouse model, the general cloning strategy to generate the triple sgRNA vectors, and the efficiency of GFP inactivation in EML4-Alk-driven autochthonous tumors.

Fields of Study & Subjects

Lung Cancer Treatments and Mutations Cancer Genomics and Diagnostics Lung Cancer Research Studies

Publication details

Publication date
12 January 2026