Supplementary Figure S2 from p53 Drives Lung Cancer Regression through a TSC2/TFEB-dependent Senescence Program

2026 Open access

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Authors: Mengxiong Wang, Kathryn T. Bieging-Rolett, Alyssa M. Kaiser, Colleen A. Brady, John H. Lockhart, Sofia Ferreira, Kha The Nguyen, Arati Rajeevan, Simone A. Evans, Tianyu Zhao, Nitin Raj, Arielle Elkrief
+7 more Sam E. Tischfield, Marc Ladanyi, Michael G. Ozawa, Nam Q. Bui, Christopher T. Chen, Elsa Renee Flores, Laura Donatella Attardi
DOI: 10.1158/2159-8290.31276764
Cited by: 0

Abstract

Supplementary Figure S2 shows that restoration of p53wt or p5353,54 induces LUAD regression and mild apoptosis in vivo.

Fields of Study & Subjects

Telomeres Telomerase and Senescence Cancer-related Molecular Pathways Autophagy in Disease and Therapy

Publication details

Publication date
6 February 2026