Supplementary Figure S10 from p53 Drives Lung Cancer Regression through a TSC2/TFEB-dependent Senescence Program

Mengxiong Wang; Kathryn T. Bieging-Rolett; Alyssa M. Kaiser; Colleen A. Brady; John H. Lockhart; Sofia Ferreira; Kha The Nguyen; Arati Rajeevan; Simone A. Evans; Tianyu Zhao; Nitin Raj; Arielle Elkrief; Sam E. Tischfield; Marc Ladanyi; Michael G. Ozawa; Nam Q. Bui; Christopher T. Chen; Elsa Renee Flores; Laura Donatella Attardi

doi:10.1158/2159-8290.31276773

Supplementary Figure S10 from p53 Drives Lung Cancer Regression through a TSC2/TFEB-dependent Senescence Program

2026 Open access

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Authors: Mengxiong Wang, Kathryn T. Bieging-Rolett, Alyssa M. Kaiser, Colleen A. Brady, John H. Lockhart, Sofia Ferreira, Kha The Nguyen, Arati Rajeevan, Simone A. Evans, Tianyu Zhao, Nitin Raj, Arielle Elkrief

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Sam E. Tischfield, Marc Ladanyi, Michael G. Ozawa, Nam Q. Bui, Christopher T. Chen, Elsa Renee Flores, Laura Donatella Attardi

DOI: 10.1158/2159-8290.31276773

Cited by: 0

Abstract

Supplementary Figure S10 shows that treatment of wild-type p53-expressing cells with an MDM2 antagonist across contexts.

Fields of Study & Subjects

Cancer-related Molecular Pathways Telomeres Telomerase and Senescence Autophagy in Disease and Therapy

Publication details

Publication date: 6 February 2026