Figure S5 from Glucocorticoids Unleash Immune-dependent Melanoma Control through Inhibition of the GARP/TGFβ Axis

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Authors: Charles H. Earnshaw, Poppy Dunn, Shih‐Chieh Chiang, Agrin Moeini, Maria A. Koufaki, Eduardo Bonavita, Massimo Russo, Laëtitia Nebot-Bral, Kimberley Hockenhull, Erin Richardson, Anna Pidoux, Charlotte R. Bell
+12 more Alexander R. Baker, Richard Reeves, Robert Sellers, Sudhakar Sahoo, Victoria Elisabeth Richardsdot Fife, Matthew G. Roberts, Theophile Bigirumurame, Caroline Dive, Julia Newton‐Bishop, Jérémie Nsengimana, Christopher E.M. Griffiths, Santiago Zelenay
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Abstract

Supplementary Figure 5. CD8+ T cell activity correlates with extent of GCinduced tumor shrinkage, and Treg depletion does not phenocopy GC treatment.

Fields of Study & Subjects

Cancer Immunotherapy and Biomarkers T-cell and B-cell Immunology TGF-β signaling in diseases

Publication details

Publication date
6 February 2026