Supplementary Video 6 from Screening for Tumor Microtube–Targeting Drugs Identifies PKC Modulators as Multipotent Inhibitors of Glioblastoma Progression

2026 Open access

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Authors: Daniel Domínguez Azorín, Dirk C. Hoffmann, Nils R. Hebach, Erik Jung, David Hausmann, Miriam Ratliff, Ling Hai, Sandra Horschitz, Ammar Jabali, Matthias Osswald, Matthia A. Karreman, Tobias Kessler
+18 more Susann Wendler, Chanté D. Mayer, Cathrin Löb, Pascal Lehnert, Gina Cebulla, Denise Reibold, Rajiv K. Khajuria, Pino Bordignon, Andreas E. Moor, Tim Holland-Letz, Jill Reckless, Nigel G. Ramsden, David Grainger, Anna Kreshuk, Philipp Koch, Wolfgang Wick, Sophie Heuer, Frank Winkler
DOI: 10.1158/2159-8290.31296572
Cited by: 0

Abstract

Live-cell confocal Ca2+ imaging of patient-derived glioblastoma cells (S24) within a hGliCS. Ca2+ dynamics were monitored using the Twitch Ca2+ reporter under DMSO control conditions. The video captures real-time Ca2+ activity within the hGliCS network

Fields of Study & Subjects

Glioma Diagnosis and Treatment Protein Kinase Regulation and GTPase Signaling Cancer Cells and Metastasis

Publication details

Publication date
9 February 2026
Language
EN