Senescence as the Next Frontier in Cancer Research: Navigating the Rising Tide of Geriatric Oncology

Cancer Discovery 2026

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Authors: Tianxing Zhou, Jingrui Yan, Yu Zhang, Fanyue Shao, J Xu, Tinghai Hu, Guohua Mao, Shangheng Shi, Yaqi Zhang, Jihui Hao
DOI: 10.1158/2159-8290.cd-25-2086
Cited by: 2
References: 13

Abstract

The global demographic shift toward an aging population has positioned cancer as a preeminent challenge in public health, with the incidence of most malignancies increasing precipitously with advancing age. By targeting the bidirectional nexus of cancer and aging, we can pioneer precision interventions to improve outcomes for the growing geriatric oncology population.

Fields of Study & Subjects

Telomeres Telomerase and Senescence Frailty in Older Adults Genetics Aging and Longevity in Model Organisms

Publication details

Journal / source
Cancer Discovery
Publisher
American Association for Cancer Research (AACR)
Volume
16
Issue
2
Pages
207–212
Publication date
6 February 2026
Language
EN