Randomized Trial Links Time of Day to Immunotherapy Success

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Abstract

Morning administration of checkpoint inhibitors significantly extended survival in patients with advanced non-small cell lung cancer, in the first randomized trial of immunotherapy timing. The results provide prospective support for aligning treatment with circadian biology as a simple way to improve cancer outcomes.

Fields of Study & Subjects

Cancer Immunotherapy and Biomarkers Circadian rhythm and melatonin Lung Cancer Diagnosis and Treatment

Publication details

Journal / source
Cancer Discovery
Volume
16
Issue
3
Pages
OF1–OF1
Publication date
2 February 2026
Language
EN