Feline Cancers: Cat-aloging the Mutational Landscape
Abstract
Targeted sequencing of nearly 500 paired tumor-normal cat tissue samples, representing 13 cancers, has uncovered strong similarities with the human oncogenome, including recurrently mutated TP53 as a driver of multiple tumor types. This is the first time the domestic feline oncogenome has been comprehensively characterized, and the human parallels support utilizing cats more frequently in comparative oncology.
Fields of Study & Subjects
Veterinary Oncology Research
Cancer Genomics and Diagnostics
Cancer-related Molecular Pathways
Publication details
- Journal / source
- Cancer Discovery
- Volume
- 16
- Issue
- 5
- Pages
- OF1–OF1
- Publication date
- 3 March 2026
- Language
- EN