More Questions Than Answers in Trial of GRAIL’s Galleri
Abstract
The NHS-Galleri trial, the first randomized, controlled trial of the multi-cancer early detection test Galleri, found that the test from GRAIL did not meet its primary endpoint, a reduction in late-stage cancers. Researchers say the result could be a consequence of the trial design, which used a surrogate endpoint rather than cancer-specific mortality, the standard measure.
Fields of Study & Subjects
Global Cancer Incidence and Screening
Prostate Cancer Diagnosis and Treatment
Pancreatic and Hepatic Oncology Research
Publication details
- Journal / source
- Cancer Discovery
- Publisher
- American Association for Cancer Research (AACR)
- Volume
- 16
- Issue
- 5
- Pages
- OF1–OF1
- Publication date
- 12 March 2026
- Language
- EN