Figure S4 from Circulating Neoantigen- and Viral Oncoprotein–Specific CD8+ T Cells Share a Transcriptional Signature

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Authors: Saumya Jani, Tomas Bencomo, Carolyn Shasha, Thomas H. Pulliam, Ana Jojic, Candice D. Church, Ted A. Gooley, David M. Koelle, Evan William Newell, Paul Nghiem
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Abstract

Supplemental Figure S4. Alternate methods of identifying cluster-defining genes and calculating gene expression scores do not yield greater AUC, sensitivity, or specificity for identifying MCPyV-specific T cells. Black dashed line represents SPoTT performance using threshold of 0.34.

Fields of Study & Subjects

T-cell and B-cell Immunology vaccines and immunoinformatics approaches CAR-T cell therapy research

Publication details

Publication date
8 January 2026