Figure S2 from Targeting SALL4 with an HLA Class I–Restricted TCR for Cancer Immunotherapy

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Authors: Myriam Ben Khelil, Maxime Fredon, Nawfel Adib, Adeline Bouard, Marie Perchaud, Syrine Abdeljaoued, Charles-Frédéric Mantion, Kamal Asgarov, Philippe Guillaume, Laurie Spehner, Evan Seffar, Marjorie Labesse
+13 more Angélique Vienot, Virginie Mougey, Mathieu Gonçalves-Venturelli, Sara Bobisse, Alexandre Harari, Camilla Jandus, Francine Garnache‐Ottou, Delphine Binda, Olivier Adotévi, Yann Godet, Marie Kroemer, Christophe Borg, Romain Loyon
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Abstract

Expression of SALL4-TCR in Jurkat TCR KO CD8+ T cells via mRNA electroporation. Representative FACS SALL4-teramer staining on Jurkat TCR KO CD8+ T cells electroporated with mRNA encoding α and β subunits for the SALL4-TCR (right) or an irrelevant-TCR (middle). Mock electroporated cells (no mRNA, left) were used for negative control.

Fields of Study & Subjects

Renal and related cancers CAR-T cell therapy research Acute Lymphoblastic Leukemia research

Publication details

Publication date
8 January 2026