Supplementary Figure S9 from T-cell Subset Features and Distributions Evolve across the Colorectal Precancer–Cancer Spectrum

Supplementary Figure S9. The combined T-cell status of precursor and carcinoma tissue categories in relation to anatomic location. (A-B) CD3+CD4+ and CD3+CD8+ T-cell densities in overall tissue regions stratified by anatomic location. (C-D) CD3+CD4+FOXP3+ and CD3+CD8+FOXP3+ T-cell densities in overall tissue regions stratified by anatomic location. P values were calculated with the Mann-Whitney U test (Wilcoxon rank-sum test) as compared to colorectal normal mucosa near precursor lesions (Normal mucosa) and carcinoma with proficient mismatch repair (pMMR). ***: P