Supplementary Figure S7 from T-cell Subset Features and Distributions Evolve across the Colorectal Precancer–Cancer Spectrum

Supplementary Figure S7. (A-D) Density of CD3+CD4+ and CD3+CD8+ T cells in intraepithelial and lamina propria propria/stromal regions across normal mucosa, non-serrated and serrated precursors, and carcinoma stratified by American Joint Committee on Cancer (AJCC) stage and mismatch repair (MMR) status. P values were calculated with Mann-Whitney U test (Wilcoxon rank-sum test) as compared to colorectal normal mucosa near precursor lesions (normal), carcinoma with AJCC stage II-IV (CA stage II-IV), and carcinoma with proficient mismatch repair (CA pMMR). ***: P