Supplementary Figure S4 from T-cell Subset Features and Distributions Evolve across the Colorectal Precancer–Cancer Spectrum

Yasutoshi Takashima; Andressa Dias Costa; Naohiko Akimoto; Tomotaka Ugai; Phoenix D. Bell; Juha P. Väyrynen; Jason L. Hornick; Mari A. Mino-Kenudson; Yuxue Zhong; Satoko Ugai; Koichiro Haruki; Qian Yao; Kosuke Matsuda; Mayu Higashioka; Daniel D. Buchanan; Amanda I. Phipps; Ulrike Peters; Marios Giannakis; Mingyang Song; Andrew Tan Chan; Charles S. Fuchs; Jonathan Andrew Nowak; Shuji Ogino

doi:10.1158/2326-6066.31028282

Supplementary Figure S4 from T-cell Subset Features and Distributions Evolve across the Colorectal Precancer–Cancer Spectrum

2026 Open access

Read full text

Authors: Yasutoshi Takashima, Andressa Dias Costa, Naohiko Akimoto, Tomotaka Ugai, Phoenix D. Bell, Juha P. Väyrynen, Jason L. Hornick, Mari A. Mino-Kenudson, Yuxue Zhong, Satoko Ugai, Koichiro Haruki, Qian Yao

+11 more

Kosuke Matsuda, Mayu Higashioka, Daniel D. Buchanan, Amanda I. Phipps, Ulrike Peters, Marios Giannakis, Mingyang Song, Andrew Tan Chan, Charles S. Fuchs, Jonathan Andrew Nowak, Shuji Ogino

DOI: 10.1158/2326-6066.31028282

Cited by: 0

Abstract

Supplementary Figure S4. T-cell densities (/mm2) in the overall region (intraepithelial + lamina propria/stromal regions) based on the subcellular-localized CD3+ (total T-cell marker) fluorescence signals across 15 precursor and 10 carcinoma tissue microarray slides from the Health Professionals Follow-up Study, Nurses’ Health Study, and Nurses’ Health Study II.

Fields of Study & Subjects

Cancer Immunotherapy and Biomarkers Microscopic Colitis Cancer Stress Anesthesia and Immune Response

Publication details

Publication date: 8 January 2026