Supplementary Figure S3 from T-cell Subset Features and Distributions Evolve across the Colorectal Precancer–Cancer Spectrum

Yasutoshi Takashima; Andressa Dias Costa; Naohiko Akimoto; Tomotaka Ugai; Phoenix D. Bell; Juha P. Väyrynen; Jason L. Hornick; Mari A. Mino-Kenudson; Yuxue Zhong; Satoko Ugai; Koichiro Haruki; Qian Yao; Kosuke Matsuda; Mayu Higashioka; Daniel D. Buchanan; Amanda I. Phipps; Ulrike Peters; Marios Giannakis; Mingyang Song; Andrew Tan Chan; Charles S. Fuchs; Jonathan Andrew Nowak; Shuji Ogino

doi:10.1158/2326-6066.31028285

Supplementary Figure S3 from T-cell Subset Features and Distributions Evolve across the Colorectal Precancer–Cancer Spectrum

2026 Open access

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Authors: Yasutoshi Takashima, Andressa Dias Costa, Naohiko Akimoto, Tomotaka Ugai, Phoenix D. Bell, Juha P. Väyrynen, Jason L. Hornick, Mari A. Mino-Kenudson, Yuxue Zhong, Satoko Ugai, Koichiro Haruki, Qian Yao

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Kosuke Matsuda, Mayu Higashioka, Daniel D. Buchanan, Amanda I. Phipps, Ulrike Peters, Marios Giannakis, Mingyang Song, Andrew Tan Chan, Charles S. Fuchs, Jonathan Andrew Nowak, Shuji Ogino

DOI: 10.1158/2326-6066.31028285

Cited by: 0

Abstract

Supplementary Figure S3. Identification of distinct T-cell subsets via the combinational expression of T-cell markers (membrane CD3, membrane CD4, membrane CD8, membrane CD45RA, membrane CD45RO, nucleus FOXP3), cell cycle marker (nucleus MKI67), epithelial marker (cytoplasm KRT), and DNA marker (nucleus DAPI) at single-cell resolution. Scale bar: 2.5 (μm).

Fields of Study & Subjects

Cancer Immunotherapy and Biomarkers Single-cell and spatial transcriptomics T-cell and B-cell Immunology

Publication details

Publication date: 8 January 2026