Figure S9 from RAS(ON) Multiselective Inhibition Drives Antitumor Immunity in Preclinical Models of NRAS-Mutant Melanoma

Supplemental Figure 9: The RMC-7977 + anti-PD1 combination reprograms the tumor microenvironment to a more pro-inflammatory state. Violin plot showing the distribution of antigen presenting cells score across different myeloid cell populations identified by single-cell RNA sequencing. Each violin represents a distinct cell type, as indicated on the x-axis, and the width of each shape represents the density of cells at a given expression level of APC1. The y-axis represents normalized expression values. Colors correspond to cell identities as shown in the legend on the right side.