Figure S1 from RAS(ON) Multiselective Inhibition Drives Antitumor Immunity in Preclinical Models of NRAS-Mutant Melanoma

Supplemental Figure 1: RMC-7977 leads to alterations in phospho-RTK and cytokine signaling. (A) Western Blot of phospho-ERK and AKT in SW1 cells treated with 8nM of RMC-7977 for 1-72h and semi-quantification graphs, n=2. (B) Western Blot of phospho-ERK and AKT in IPC298 cells treated with 3nM of RMC-7977 for 1-72h and semi-quantification graphs, n=2. One-way ANOVA was performed followed by Tukey’s multiple comparisons test: *p