Supplementary Figure S6 from Lymphotropic Virotherapy Induces DC and High Endothelial Venule Inflammation, Promoting the Antitumor Efficacy of Intratumor Virus Administration

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Authors: Amei Ludwig, Zachary P. McKay, Griffin P. Carter, Mark A. Katz, Georgia Howell, Vaibhav Jain, Stephanie Arvai, Dirk P. Dittmer, Darell D. Bigner, David M. Ashley, Madison L Shoaf, Annick Desjardins
+3 more Simon G. Gregory, Michael C. Brown, Matthias Gromeier
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Abstract

Supplementary Figure S6. a-c, Extended data relating to Figure 5. Umap of snRNAseq of combined samples from three intervals (see Figure 5D); individual cell types are labeled (a). Umap of cells identified as T cells in a; individual subsets are labeled (see Supplementary Table S2 for extended data) (b). Proportion of cell types identified in a by time point (c). d, e, Gating strategy used (extended data relating to Figure 5E, F).

Fields of Study & Subjects

Virus-based gene therapy research Immunotherapy and Immune Responses Cancer Immunotherapy and Biomarkers

Publication details

Publication date
3 February 2026