Supplemental Table 3 from WTX-124, a Conditionally Activated Wild-Type IL2, Maximizes the Therapeutic Index of IL2, Unlike “Non-Alpha” Muteins

2026 Open access

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Authors: Christopher J. Nirschl, Kulandayan K. Subramanian, Heather R. Brodkin, Celesztina Domonkos, Connor J. Dwyer, Daniel J. Hicklin, RANDI E. ISAACS, Nesreen S. Ismail, Julie LePrevost, Yuka Lewis, Kristin R. Morris, Cynthia Seidel‐Dugan
+5 more Zoe Steuert, Jenna M. Sullivan, Sameer S. Chopra, Andrés Salmerón, William M. Winston
DOI: 10.1158/2326-6066.31484110
Cited by: 0

Abstract

Parameters Used in the Modeling of the Cytokine IL-2. A table of the values used to inform the model predictions. Table values were either determined experimentally within reason, or were identified based on the cited source.

Fields of Study & Subjects

Monoclonal and Polyclonal Antibodies Research Cytokine Signaling Pathways and Interactions T-cell and B-cell Immunology

Publication details

Publication date
4 March 2026
Language
EN