Supplemental Figure 5 from WTX-124, a Conditionally Activated Wild-Type IL2, Maximizes the Therapeutic Index of IL2, Unlike “Non-Alpha” Muteins

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Authors: Christopher J. Nirschl, Kulandayan K. Subramanian, Heather R. Brodkin, Celesztina Domonkos, Connor J. Dwyer, Daniel J. Hicklin, RANDI E. ISAACS, Nesreen S. Ismail, Julie LePrevost, Yuka Lewis, Kristin R. Morris, Cynthia Seidel‐Dugan
+5 more Zoe Steuert, Jenna M. Sullivan, Sameer S. Chopra, Andrés Salmerón, William M. Winston
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Abstract

IFNγ production in PBMC donors with IL-2 stimulation

Fields of Study & Subjects

T-cell and B-cell Immunology Monoclonal and Polyclonal Antibodies Research Immunotherapy and Immune Responses

Publication details

Publication date
4 March 2026
Language
EN