Supplemental Figure 3 from T-cell Priming by High-Avidity Neoantigens in Lymph Nodes Augments Adoptive Immunotherapy

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Authors: Megen C Wittling, Amalia M. Rivera-Reyes, Megan M. Wyatt, Anna C. Cole, Aubrey S. Smith, Guillermo O. Rangel Rivera, James H. Carmouche, Kailey G. Diatikar, Ayana T. Ruffin, Michael B. Ware, Frances Jenkins Bennett, Connor J. Dwyer
+5 more Riley M.F. Pihl, Soundharya Kumaresan, Gregory B. Lesinski, Chrystal Mary Paulos, Hannah M. Knochelmann
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Abstract

Supplemental Figure 3: Survival Analysis in the SKCM Cohort. (A) The top 10 genes that were significantly upregulated in neoantigen tumors day 5 post-ACT were evaluated for their impact on survival in the TCGA SKCM cohort. Overall Survival with a Median Group Cutoff was used. Hazards Ratio was calculated based on the PH model. 95% confidence interval is displayed as a dotted line. Graphs made using GEPIA.

Fields of Study & Subjects

Cancer Immunotherapy and Biomarkers Immunotherapy and Immune Responses T-cell and B-cell Immunology

Publication details

Publication date
4 March 2026
Language
EN