Supplementary Figure S1-S8 from Intra-Leukemic Interferon Signaling Suppresses Expansion and Mediates Chemoresistance in Human AML

Supplementary Figure 1 shows Suppressed leukemia cells maintain disease-initiating capacity. Supplementary Figure 2 shows iAML isogenic competition model with fluorescent G0 reporter. Supplementary Figure 3 shows Oxidative phosphorylation does not account for suppression Supplementary Figure 4 shows IFN signaling inhibits suppressed samples Supplementary Figure 5 shows BST2 contributes to IFN-mediated AML suppression. Supplementary Figure 6 shows IFN signaling is associated with chemoresistance in experimental models. Supplementary Figure 7 shows IFN signaling is associated with chemoresistance in primary AML patient samples. Supplementary Figure 8 shows Blocking IFN signaling affects cycling and chimerism of patient samples.