Supplemental Figure 5 from Tandem Duplications in UBTF Create XPO1-Dependent Nuclear Export Signals that Reveal a Leukemic Therapeutic Dependency

Juan Martin Barajas; Aaron H. Phillips; Jina Wang; Melvin E. Thomas; Lisett Contreras; Masayuki Umeda; Ryan Hiltenbrand; Elizabeth Caldwell; Michael P. Walsh; Guangchun Song; Lauren Ezzell; Kelly A. Churion; Tamara Westover; Emily H. Xiong; Chandra Rolle; Jamila Moore; Josi Lott; Sandi Radko-Juettner; Amit Kumar; Wenjie Qi; Beisi Xu; Evangelia K. Papachristou; Clive S. D’Santos; Jing Ma; Burgess B. Freeman; Laura J. Janke; Richard W. Kriwacki; Jeffery M. Klco

doi:10.1158/2643-3230.31046986

Supplemental Figure 5 from Tandem Duplications in UBTF Create XPO1-Dependent Nuclear Export Signals that Reveal a Leukemic Therapeutic Dependency

2026 Open access

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Authors: Juan Martin Barajas, Aaron H. Phillips, Jina Wang, Melvin E. Thomas, Lisett Contreras, Masayuki Umeda, Ryan Hiltenbrand, Elizabeth Caldwell, Michael P. Walsh, Guangchun Song, Lauren Ezzell, Kelly A. Churion

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Tamara Westover, Emily H. Xiong, Chandra Rolle, Jamila Moore, Josi Lott, Sandi Radko-Juettner, Amit Kumar, Wenjie Qi, Beisi Xu, Evangelia K. Papachristou, Clive S. D’Santos, Jing Ma, Burgess B. Freeman, Laura J. Janke, Richard W. Kriwacki, Jeffery M. Klco

DOI: 10.1158/2643-3230.31046986

Cited by: 0

Abstract

Depicts genomic occupancy of HA-tagged UBTF constructs and XPO1 at rDNA loci in cbCD34⁺ cells using CUT&RUN.

Fields of Study & Subjects

Acute Myeloid Leukemia Research Nuclear Structure and Function Genomics and Chromatin Dynamics

Publication details

Publication date: 12 January 2026