Figure 3 from Cell State Transitions Drive the Evolution of Disease Progression in B-Lymphoblastic Leukemia

Samples from patients in molecular remission. A, Chord diagram illustrating the mean transition matrix across all patients. The chord is organized into four sections (CD34+/CD38−, CD34+/CD38+, CD34−/CD38+, and CD34−/CD38−), with the size of each chord proportional to the magnitude of the outgoing transition rate. Chords are ordered (clockwise) by the magnitude of outgoing transition by each section for visual interpretation, and each bi-directional chord is colored by which is greater: Mij or Mji. B, Chord diagram shown for each individual patient sample. Central numbers indicate sample ID, corresponding to the Morpheus diagram in Fig. 2I. Numbers at the top right of each diagram indicate the number of samples available for that patient.