Supplementary Figure S8 from Combining Brigatinib with mTOR Inhibition to Effectively Treat NF2-SWN–Associated and Sporadic NF2-Deficient Meningiomas

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Authors: Long‐Sheng Chang, Janet L. Oblinger, Lai Man Natalie Wu, Cecelia Miller, Sarah S. Burns
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Abstract

Figure S8. The brigatinib+INK128 combination, but not the monotherapies, markedly downregulated several YAP target genes in treated AG-NF2-Men cells.

Fields of Study & Subjects

Meningioma and schwannoma management Hippo pathway signaling and YAP/TAZ Neurofibromatosis and Schwannoma Cases

Publication details

Publication date
27 January 2026