Figure 4 from Characterization of the Immunogenomic Landscape of Ovarian Cancer Uncovers a Distinct Subset of Endometroid Tumors Associated with High CST2 Expression and a Favorable Prognosis

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Authors: James Boyle, Jan Maciej Zaucha, Felicia Ng, Andreas Spitzmüller, Miljenka Vuko, Felix J. Segerer, Monica Azqueta-Gavaldon, Marco Testori, Amelia Raymond, Barrett R. B. Nuttall, Andrea Ennio Storti, Sakshi Gulati
+9 more Shaan Gill, Michael J. Surace, Paola Marco‐Casanova, Emma V. Jones, Ben S. Sidders, Jorge Sergio Reis-Filho, Maurizio Scaltriti, Anita Semertzidou, Helen K. Angell
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Abstract

Plots detailing the subgroup of endometrioid samples. A, Uniform Manifold Approximation and Projection (UMAP) plot of the samples according to their position in latent variable space, showing clearly the subgroup of endometrioid patients discussed in the main text. B, Expression of CST2 for endometrioid samples stratified by subgroup membership. C, Oncoprint of selected genes for endometrioid samples stratified by subgroup membership. D, Survival curves for endometrioid samples stratified by subgroup membership. E, Density of proliferating tumor cells and (F) MHC-II antigen presentation expression for endometrioid samples stratified by subgroup membership.

Fields of Study & Subjects

Ovarian cancer diagnosis and treatment Endometrial and Cervical Cancer Treatments Gene expression and cancer classification

Publication details

Publication date
28 January 2026