Supplementary Figure S1 from Novel Syngeneic Cell Lines for Studying High-Risk BRAFV600E-Driven Colorectal Cancer In Vivo

2026 Open access

Read full text
Authors: Jasmin Traichel, Ariane Metzger, Maria Walz, Reinhild Feuerstein, Nadine Wohlfeil, Patrick Metzger, Lisa Marx, Célia Asdih, Agnes Lindenthal, Alina Seger, Jule Schrimpf, Luigi L. Nardella
+7 more Silke Kowar, Ian J. Frew, Sebastian Halbach, Rebecca Kesselring, Melanie Boerries, Ricarda Griffin, Tilman Brummer
DOI: 10.1158/2767-9764.31343746
Cited by: 0

Abstract

Supplementary Figure S1 shows that the expression of BRAFV600E and p53R172H as well as Apc deficiency induces distinct morphological changes and transcriptome profiles in murine organoids.

Fields of Study & Subjects

Colorectal Cancer Treatments and Studies Genetic factors in colorectal cancer Melanoma and MAPK Pathways

Publication details

Publication date
16 February 2026
Language
EN