The Impact of Surgical Intervention on the Survival of Primary Head and Neck MALT Lymphoma

INTRODUCTION: Primary head and neck mucosa-associated lymphoid tissue lymphoma (HN-MALT) is a rare B-cell lymphoma whose epidemiology, clinical features, and treatment strategies remain unclear. METHODS: We conducted a retrospective analysis of HN-MALT data from the Surveillance, Epidemiology, and End Results (SEER) database (2000-2021) and compared the incidence and mortality rates among age groups. The Kaplan-Meier was used to determine the overall survival (OS) and lymphoma-specific survival (LSS). Prognostic factors were identified using univariate and multivariate Cox regression models. RESULTS: In a cohort of 2,517 patients, the annual incidence rate of HN-MALT in patients ≥60 years old was higher than that in those