Testicular Volume of 4 mL Is Not an Appropriate Marker of Pubertal Onset in a Subset of Boys Born Small for Gestational Age

Sexual Development 2026 Open access

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Authors: Sofía Suco, Patricia Bedecarrás, Marı́a Gabriela Ballerini, María Gabriela Ropelato, Debora Giselle Braslavsky, María Eugenia Rodriguez, Ana Claudia Keselman, Rodolfo Alberto Rey, Romina P. Grinspon
DOI: 10.1159/000551056
Cited by: 0
References: 29

Abstract

INTRODUCTION: Considering that testicular volume (TV) is probably not an adequate marker of pubertal onset in boys born small for gestational age (SGA), we aimed to describe the progression of pubertal clinical and biochemical characteristics, comparing the trajectory of TV with other parameters as markers of pubertal onset in boys born SGA. METHODS: We performed a retrospective, descriptive study of a cohort of boys born SGA with longitudinal follow-up. We determined the TV at the time when serum AMH decreased ≥30% or LH attained 0.35 IU/L. RESULTS: Thirty boys born SGA were included: 16 of 30 (53.3%) had LH ≥0.35 IU/L and 7 of 24 boys (29.2%) had a decline ≥30% in serum AMH with a TV

Fields of Study & Subjects

Hypothalamic control of reproductive hormones Sexual Differentiation and Disorders Sperm and Testicular Function

Publication details

Journal / source
Sexual Development
Volume
20
Issue
1-6
Pages
58–67
Publication date
26 February 2026
Language
EN