The Use of a Xenogeneic Collagen Matrix in Combination with Coronally Advanced Flap for Treating Multiple Adjacent Gingival Recessions: A Prospective Clinical Study

This prospective study assesses the clinical outcomes of a novel xenogeneic acellular dermal matrix (ADM) for the treatment of multiple adjacent gingival recessions. Thirteen patients with 25 RT1 and 10 RT2 defects were treated using CAF + ADM. Clinical outcomes included recession reduction (RR), mean root coverage (MRC), complete root coverage (CRC), change in keratinized tissue width (KTW), and aesthetic evaluation (RES score). Patients' pain perception was evaluated through a visual analog scale at day 1 and 7 post-surgery. At 12 months post-surgery, the mean residual recession was 0.65 ± 0.87 mm, with an RR of 1.8 ± 1.1 mm. The MRC was 70.5 ± 54.2%, and CRC was achieved in 62.9% of cases. The total RES score was 7.5 ± 2.5. For RT1 and RT2, MRC was 71.3 ± 61.3% and 68.7 ± 32.4%, with a CRC of 72.0% and 40.0%, respectively. These findings indicate favorable improvement in mucogingival parameters over 12 months, suggesting that the use of ADM in combination with a coronally advanced flap may represent a viable therapeutic option for root coverage.