Clinical Spectrum of Children With Parvovirus B19–Associated Acute Myocarditis

Circulation 2026

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Authors: Enrico Ammirati, Giacomo Veronese, Francesca Raimondi, G Annoni, Domenico Sirico, Francesco Bianco, Alessio Franceschini, Gessica Ingrasciotta, Giovanni Meliota, Guglielmo Capponi, Isabella Pellicioli, Gaia Chiesa
+32 more C. Beretta, Giada Colombo, Giovanni Di Salvo, Sandra Nonini, Francesca Aresta, Luca Ragni, Tammam Hasan, Maurizio Brighenti, Giovanna Travi, Olivia Leoni, Paul Stefan Vrabie, Michele Ercolanoni, Giuseppe Limongelli, Emanuele Monda, Maria Giovanna Russo, Alessandra Corato, Elena Reffo, Valentina Bucciarelli, Sergio Filippelli, Susanna Breviario, Carlo Pace Napoleone, Ugo Vairo, Maristella Lombardi, Nadia Assanta, Pietro Marchese, Paolo Ferrero, Flavio Ribichini, Andrea Garascia, Michele Giovanni Mondino, Antonio Amodeo, Rachele Adorisio, Ezio Bonanomi
DOI: 10.1161/circulationaha.125.075943
Cited by: 5
References: 26

Abstract

BACKGROUND: Parvovirus B19 is a DNA virus transmitted via respiratory droplets, commonly causing erythema infectiosum in children but also implicated in acute myocarditis. In 2024, an outbreak of parvovirus B19 infections was reported across Europe and the United States. Despite growing awareness, data on the clinical features and outcomes of children with parvovirus B19–associated acute myocarditis remain limited. METHODS: This multicenter retrospective observational study reviewed medical records of pediatric patients (

Fields of Study & Subjects

Parvovirus B19 Infection Studies Viral Infections and Immunology Research Aortic Thrombus and Embolism

Publication details

Journal / source
Circulation
Publisher
Ovid Technologies (Wolters Kluwer Health)
Volume
153
Issue
10
Pages
699–715
Publication date
5 January 2026
Language
EN