The Fontan Outcomes Network: Findings After 2 Years and 1121 Participants

Circulation 2026 Open access

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Authors: Thomas M. Glenn, Nadine A. Kasparian, Shahnawaz Amdani, David Renaud, Michael V. DiMaria, Jennifer Berano Teh, David M. Leone, Arjun Mahendran, Nancy A. Pike, S Dolgner, Andrew L. Cheng, Rahul H. Rathod
+75 more Sumeet S. Vaikunth, Surendranath Veeram Reddy, Rohith Vanam, Jeff Theobald, K. Schumacher, Sarah A. Hummel, J. Conway, David J. Goldberg, Dala Zakaria, Sarah Clauss, Divya Suthar, Roni Jacobsen, Evonne Morell, John C. Dykes, Angela Weingarten, Deepti P. Bhat, Benjamin E. Reinking, Tarek Alsaied, Carole Lannon, Kiona Y. Allen, Jeffrey Anderson, Lacie B. Patterson, Denise Brown, Richard James, Jack Rychik, Alexander R. Opotowsky, Jeremy T. Affolter, Diane Aguero, Alaa Aljiffry, Saleem Almasarweh, Julie Bonn, Jamie Colombo, Paul Critser, Meghan Didier, Kathryn Dodds, Francine Erenberg, David M. Finkelstein, Therese M. Giglia, Salil Ginde, M Gord, Joseph N. Graziano, Jessica Haley, Stephanie S. Handler, Jesse Hansen, Anyir Hsieh, Alicia K. Hutson, Natalie Jayaram, Omar Khalid, Matthew S. Lemler, Andrew S. Mackie, Amanda McCormick, Kimberly L. Moore, Lakshmi Nagaraju, Melanie Parent, Trudy Pierick, Michelle Ploutz, Pierangelo Renella, Kate Robb, Nancy Rudd, Ilana Schwartz, Kavisha Shah, Rachel J. Shustak, Jose Silva Sepulveda, Megan Soohoo, Eileen Stewart, Michelle Steltzer, Sunderji Sg, Karen Texter, Rocky Tsang, Casey Vogel, Jodie K. Votava-Smith, Justin Weigand, Alicia Wilmoth, Fred Wu, Adel K. Younoszai
DOI: 10.1161/circulationaha.125.078152
Cited by: 4
References: 33

Abstract

BACKGROUND: Survival after Fontan palliation for single ventricle heart disease has improved substantially, yet the long-term trajectory remains poorly defined. The Fontan Outcomes Network, a learning health network of 38 congenital heart centers in the United States and Canada, was established to address this gap. We report baseline characteristics and early findings from the first 1121 participants enrolled in this prospective clinical registry. METHODS: We performed a cross-sectional analysis of individuals who had undergone Fontan palliation enrolled in the Fontan Outcomes Network from August 2022 through August 2024. Demographic, clinical, imaging, procedural, and medication data were analyzed descriptively, overall and by age group (

Fields of Study & Subjects

Congenital Heart Disease Studies Central Venous Catheters and Hemodialysis Cardiomyopathy and Myosin Studies

Publication details

Journal / source
Circulation
Publisher
Ovid Technologies (Wolters Kluwer Health)
Volume
153
Issue
16
Pages
1182–1195
Publication date
25 March 2026
Language
EN