Interplay of Age and Sex With Clinic and Ambulatory Blood Pressure and Mortality

Hypertension 2026

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Authors: Michael Böhm, Alejandro de la Sierra, Igor Schwantke, Bernhard Haring, Ernest Vinyoles, Manuel Gorostidi, Julián Segura, Bryan Williams, Natalie Staplin, Mert Tokcan, F Mahfoud, Lucas Lauder
+3 more Susanne V. Fleig, Carolin Victoria Schneider, Luis Miguel Ruilope
DOI: 10.1161/hypertensionaha.125.26084
Cited by: 1
References: 41

Abstract

BACKGROUND: To explore associations of clinic and 24-hour ambulatory blood pressure (BP) monitoring (ABPM) with cardiovascular death (CVD), parameters were modeled for age and sex in this large cohort in primary care. METHODS: In the Spanish ABPM Registry, 59.124 patients had complete data on mortality, age, sex, and all ABPM. Office, mean, 24-hour, daytime, and nighttime systolic BP (SBP), diastolic BP, and pulse pressure (PP) were related to CVD according to age and sex and were modelled with restricted cubic splines to get trajectories. During a median of 9.7 years, 2361 patients had CVD (1229 males, 1132 females). RESULTS: Nonlinear relationships for office, 24-hour mean, daytime, and nighttime SBP, diastolic BP, and PP ( P

Fields of Study & Subjects

Blood Pressure and Hypertension Studies Health Systems Economic Evaluations Quality of Life Heart Failure Treatment and Management

Publication details

Journal / source
Hypertension
Publisher
Ovid Technologies (Wolters Kluwer Health)
Volume
83
Issue
6
Pages
e26084–e26084
Publication date
4 March 2026
Language
EN