Intensive BP Control and Cognitive Function: A Randomized Clinical Trial

Hypertension 2026 Open access

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Authors: Bin Wang, Ying Zhi Sun, Yan Li, Liyong Wu, Yue Peng, Shitian Li, Jinzhuo Ge, Liping Zhang, Lingshan Zhao, Jiangling Liu, Shuhong Su, Bing Zhang
+7 more Yaqin Liu, Xiaowen Ma, Zhaokai Zuo, Haibo Zhang, Yang Wang, Jiamin Liu, Jing Li
DOI: 10.1161/hypertensionaha.125.26572
Cited by: 1
References: 31

Abstract

BACKGROUND: The impact of intensive blood pressure (BP) control on cognitive function in East Asian populations remains uncertain. We aimed to assess the effect of a lower systolic BP target on global cognitive function in Chinese hypertensive adults. METHODS: This secondary analysis of a randomized trial involved hypertensive patients with high cardiovascular risk across 116 sites in China. Participants were assigned to receive intensive treatment (systolic BP target

Fields of Study & Subjects

Dementia and Cognitive Impairment Research Blood Pressure and Hypertension Studies Cardiovascular Health and Risk Factors

Publication details

Journal / source
Hypertension
Publisher
Ovid Technologies (Wolters Kluwer Health)
Volume
83
Issue
4
Pages
e26572–e26572
Publication date
26 February 2026
Language
EN