Burden of Potentially Undiagnosed Heart Failure With Preserved Ejection Fraction in Atrial Fibrillation and Effects of Catheter Ablation: Insights From CABANA
Abstract
Background Patients with atrial fibrillation (AF) often complain of dyspnea, raising the question that symptoms could be related to unrecognized heart failure (HF) with preserved ejection fraction (HFpEF). Methods We used the HFpEF‐age, body mass index and history of AF algorithm to estimate the probability of undiagnosed HFpEF in CABANA (Catheter Ablation vs. Antiarrhythmic Drug Therapy), and its interaction with catheter ablation on quality of life (QOL). Probable HFpEF was defined as patient‐reported dyspnea with HFpEF‐age, body mass index and history of AF probability≥75%. Absence of dyspnea or HFpEF‐age, body mass index and history of AF probability
Fields of Study & Subjects
Atrial Fibrillation Management and Outcomes
Cardiac pacing and defibrillation studies
Cardiovascular Function and Risk Factors
Publication details
- Journal / source
- Journal of the American Heart Association
- Publisher
- Ovid Technologies (Wolters Kluwer Health)
- Volume
- 15
- Issue
- 4
- Pages
- e047295–e047295
- Publication date
- 11 February 2026
- Language
- EN