Outcomes of Type B Dissection in Marfan Syndrome: The Cornell Aortic Aneurysm Registry

Journal of the American Heart Association 2026 Open access

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Authors: Nupoor Narula, R DEVEREUX, Xiaoyue Ma, Kaitlyn Trinder, Leonard N. Girardi, Jonathan W. Weinsaft, Mary J. Roman
DOI: 10.1161/jaha.125.048274
Cited by: 1
References: 28

Abstract

Background Rates of type B dissection are nearly double those of type A in Marfan syndrome. However, data surrounding clinical and surgical outcomes of type B dissection and associated life expectancy are limited. Methods We investigated outcomes and survival of type B dissection in a large, single‐center Marfan syndrome registry. Results Fifty of 362 (13.8%) patients experienced a type B dissection, with a median postdissection follow‐up of 8.9 (interquartile range, 3.9–15.4; range, 0–33.4) years. Although dissection rates were comparable in men and women (14.4% versus 13.4%, P =0.78), dissection occurred at an earlier age in men (36 versus 46 years, P =0.025). Seventeen (34.0%) patients required early (

Fields of Study & Subjects

Connective tissue disorders research Aortic Disease and Treatment Approaches Aortic aneurysm repair treatments

Publication details

Journal / source
Journal of the American Heart Association
Publisher
Ovid Technologies (Wolters Kluwer Health)
Volume
15
Issue
9
Pages
e048274–e048274
Publication date
22 April 2026
Language
EN