Abstract A078: Development of Prognostic Models and Nomograms for Independent Ambulation After Endovascular Thrombectomy in the SELECT2 Trial

Background: While endovascular thrombectomy(EVT)improved outcomes for large ischemic strokes in randomized trials, only one in three EVT patients achieved mRS 0-3. Accurate prognostication for patient selection, counseling, and management is difficult with currently available tools and not readily applicable to clinical practice. Methods: From SELECT2 randomized trial, EVT patients were analyzed. A pre-thrombectomy model using baseline, and a post-thrombectomy model with both baseline and post-procedural variables were developed through backward stepwise regression with relevant clinical and imaging variables to predict mRS 0-3. Discrimination, Hosmer Lameshow goodness of fit, calibration analyzed, 5-fold crossvalidation performed for internal validation and nomograms were developed. Results: Tissue volume with