Abstract A115: Fragmented Sleep and Delirium Incidence in Older Patients with Ischemic Stroke: A Device-Based Analysis of Sleep Continuity and Outcomes in the Hospital Setting

Introduction: Disruptions to sleep lead to a cascade of health-related consequences, particularly in the hospital environment. We investigated whether compounded burden due to repeated sleep fragmentation was associated with hospital-acquired delirium (HAD) and discharge outcomes among older acute ischemic stroke (AIS) patients. Methods: Sleep activity data were captured using continuous health monitoring devices for AIS patients (aged ≥ 70 years) treated and admitted at a 7-hospital stroke-certified system (Apr 2023 to Jul 2025). Patients were included if they screened negative for delirium upon admission and had 2+ nights of hospital stay. Nightly sleep continuity was defined if 4+ uninterrupted hours of sleep was recorded during nighttime (10PM to 5AM). Overall sleep continuity was aggregated per visit and categorized as high (>75% nights with continuous sleep), moderate (50-75%), or low (