Abstract A129: Mapping Acute Post-Stroke Aphasia: multidimensional language deficits reveal dissociable neural signatures of compensation and inhibition via resting-state fMRI

Stroke 2026

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Authors: Yumei Zhang, Zinan Yuan
DOI: 10.1161/str.57.suppl_1.a129
Cited by: 0

Abstract

Introduction: Post-stroke aphasia (PSA) affects 20–40% of stroke survivors and is characterized by heterogeneous impairments across phonological, lexical, semantic, and syntactic domains. Traditional scales largely collapse these dimensions, limiting mechanistic insights into their neural bases. Here, we combined a theory-driven language battery with multimodal rs-fMRI to delineate dissociable neural signatures of compensation and inhibition. Methods: 48 patients with acute PSA (

Fields of Study & Subjects

Neurobiology of Language and Bilingualism Functional Brain Connectivity Studies Hemispheric Asymmetry in Neuroscience

Publication details

Journal / source
Stroke
Volume
57
Issue
Suppl_1
Publication date
29 January 2026
Language
EN