Abstract DP275: Association of Plasma Biomarkers and Risk of Seizures in Pediatric Brain Arteriovenous Malformations

Stroke 2026

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Authors: Vinh Q. Nguyen, Shantel Weinsheimer, Jeffrey Nelson, Shweta Amy Chawla, Tania Davila, Ronan Esperanza, Charles E. McCulloch, Ethan A. Winkler, Nalin M. Gupta, Daniel L. Cooke, Steven W. Hetts, Yi Li
+3 more Christine K. Fox, Heather J. Fullerton, Helen Kim
DOI: 10.1161/str.57.suppl_1.dp275
Cited by: 0

Abstract

Introduction: Brain arteriovenous malformations (bAVMs) are a major cause of morbidity in pediatric patients, with seizures as the second most common presentation. The mechanisms underlying seizures in this population remain poorly understood. Circulating plasma protein biomarkers may reflect neuroinflammatory or neurovascular changes associated with seizures. We hypothesized that plasma levels of inflammatory biomarkers differ between bAVM patients with and without seizures. Methods: Blood samples were collected from 155 enrolled bAVM study participants (

Fields of Study & Subjects

Vascular Malformations Diagnosis and Treatment Epilepsy research and treatment Vascular Malformations and Hemangiomas

Publication details

Journal / source
Stroke
Volume
57
Issue
Suppl_1
Publication date
29 January 2026
Language
EN