Abstract TP155: Examining Intersectionality of Sex and Race-Ethnicity in Acute Hemorrhagic Stroke among Young Adults

Background: Although intracerebral hemorrhage (ICH) represents only ~13% of all strokes in the United States, it carries high morbidity and mortality. Data on sex-based differences in ICH remains limited. Men more often present with hypertension, while women are more likely to have vascular malformations and worse outcomes despite smaller bleeds. Black and Hispanic young adults experience higher ICH incidence and mortality than Whites, with hypertension being a key risk factor. This study explores how intersecting factors of sex and race-ethnicity relate to outcomes such as inpatient mortality and discharge disposition among young ICH patients treated at a comprehensive stroke center Methods: We identified patients aged 18–50 with non-traumatic ICH from our stroke registry between 10/2016 and 11/2019. Baseline socio-demographic, clinical characteristics, and outcomes were compared across groups. Logistic and multinomial logistic regressions were used, as appropriate, to assess predictors of mortality and discharge disposition. Results: Among 619 patients, 63.8% were male and 36.2% female. The average age of the cohort was 40.3 years (SD: 8.4). The cohort included 195 Non-Hispanic Black, 156 Non-Hispanic White, 33 Asian, 189 Hispanic, and 46 Non-Hispanic other patients. Admission creatinine ranged from 0.46–3.09 mg/dL; glucose from 76–233 mg/dL. Elevated admission glucose and creatinine were associated with increased inpatient mortality (OR=1.01, p