Abstract TP177: Disparities in Stroke-Related Mortality among U.S. Adults with Chronic Obstructive Pulmonary Disease (COPD) 1999–2023: A CDC WONDER Database Analysis

Background: Chronic obstructive pulmonary disease (COPD) and stroke remain major contributors to U.S. mortality. Although age-adjusted mortality rates (AAMRs) have declined, disparities across sex, race/ethnicity, region, and urbanization persist. Methods: We used CDC WONDER data (1999–2023) to identify deaths among adults ≥35 years with COPD (ICD-10 J40–J47) and stroke (I60.x, I61.x, I63.x, I64, I69.0, I69.1, I69.3, I69.4). A total of 324,642 deaths were included. AAMRs per 100,000 ( 2000 U.S. standard population) were calculated. Joinpoint regression estimated annual percent change (APC) and average annual percent change (AAPC) by demographic and geographic factors Results: The overall AAMR was 7.52 (95% CI: 7.39–7.65). Mortality decreased from 1999–2009 (APC −4.5%, p